Request Appt Request an Appointment Like Us Like Us on Facebook Instagram Follow Us on Instagram Reviews Read our Reviews Call Give us a Call Map View our Map

PRF Facial Rejuvenation: What Is It? How Does It Work?

August 3, 2026

Medical professional removing processed blood from centrifuge

As someone who cares about your appearance, you are no doubt interested in the latest professional beauty treatments. Some seem like passing trends, whereas others will stick around for the long haul. One approach that is gaining attention is known as platelet-rich fibrin (PRF) therapy. What exactly is it, how can it help you achieve your ideal look, and how does it work? Continue reading to find out.

What Is PRF?

PRF is the platelet-rich portion of your own blood. It also contains structural proteins, signaling molecules, and more. These components play a key role in wound healing. When you sustain a cut or another type of injury, the platelets and other key factors work together to stop the bleeding and repair the tissue.

Some orthopedic clinics and other doctors use PRF for pain reduction and to promote healing after surgery. In the world of beauty treatments, PRF can power up your skin’s natural healing abilities to reduce a range of skin concerns, including fine lines, wrinkles, scars, skin laxity, enlarged pores, dullness, and more.

How Does PRF Work?

The PRF treatment is pretty simple and easy for patients. Your care team will take a small sample of your blood and then place it in a centrifuge. The centrifuge will spin the blood at a specific speed in order to separate the portion that is rich in platelets. Next, the PRF will be injected at pre-planned positions in your face. The entire appointment may take an hour or less.

For optimal results, you may have to attend multiple sessions spaced several weeks apart. Peak results usually take 3 – 6 months, but you may start to notice a difference in your appearance after just a few weeks.

What Makes PRF Stand Out?

PRF is different from other treatments because it harnesses your body’s own ability to heal instead of relying on outside substances. It also does not use anticoagulants, which means that a fibrin matrix can form naturally after injections. This matrix, in turn, allows for the sustained release of factors that support skin health and a glowing complexion. Ultimately, PRF can lead to long-lasting results because of this unique feature.

PRF treatment is generally very safe, and you can combine it with other facial injectables, such as BOTOX or fillers, to provide even more comprehensive results.

PRF facial rejuvenation is pretty amazing! Talk to a qualified provider to learn more about it and whether it might be right for you.

Meet the Practice

Elizabeth Estes Weldon is a board-certified Advanced Practice Registered Nurse with more than a decade of experience in dermatology. She is proud to offer BOTOX, dermal fillers, and PRF facial rejuvenation. If you are interested in elevating your appearance through injectable treatments, Elizabeth and our team would be pleased to welcome you. Contact our office in Ocala at 352-433-0888.